A CARDIOVASCULAR DISEASE PREDICTION MODEL BASED ON ROUTINE PHYSICAL EXAMINATION INDICATORS USING MACHINE LEARNING METHODS: A COHORT STUDY

A Cardiovascular Disease Prediction Model Based on Routine Physical Examination Indicators Using Machine Learning Methods: A Cohort Study

BackgroundCardiovascular diseases (CVD) are currently the leading cause of premature death worldwide.Model-based early detection of high-risk populations for CVD is the key to CVD prevention.Thus, this research aimed to use machine learning (ML) algorithms to establish a CVD prediction model based on routine physical examination indicators suitable

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Influence of urban gardening conditions on the concentration of antioxidant secondary plant metabolites in kale

During the COVID-19 pandemic urban gardening became popular across the globe.Leafy vegetables Headlight Cover supplement the daily diet and contribute to consumers health.Within the last decade kale (Brassica oleracea var.sabellica L.) gained popularity in urban gardening.However, shading due to unfavourable cardinal directions may reduce plant gro

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Recent Advances in the Use of the Dimerization Strategy as a Means to Increase the Biological Potential of Natural or Synthetic Molecules

The design of C2-symmetric biologically active molecules is a subject of interest to the scientific community.It provides the possibility of discovering medicine with higher biological potential than the parent drugs.Such molecules are generally produced by classic chemistry, considering Technology Rescue Kit the shortness of reaction sequence and

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Differential diagnosis of polyneuropathies in diabetes mellitus

Diabetic polyneuropathy (DPN) is heterogeneous in its clinical course and clinical manifestations.Depending on the primary lesion of large or small nerve fibers, different onset, course and clinical manifestations of polyneuropathy are possible.In patients with diabetes, the incidence of associated lesions of the peripheral nervous system is high.W

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Deep R-gene discovery in HLB resistant wild Australian limes uncovers evolutionary features and potentially important loci for hybrid breeding

Huanglongbing (HLB) is a devastating citrus disease that threatens the citrus industry worldwide.HLB is associated with the bacteria Candidatus Liberibacter asiaticus (CLas) and as of today, there are no tools for economically viable disease management.Several wild Australian limes have been identified to be HLB resistant and their resistance is hy

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